Research & Consultancy

Thrust Areas of Research

Biodegradation & Bioremediation : Monitoring of polyaromatic hydrocarbons (PAHs) in environment; Biodegradation and elucidation of metabolic pathways of high molecular weight PAHs; Bioremediation protocol development for PAHs.

Wild Edible Fruits and Herbals : Determination of polyphenols, antioxidant, anti-cancer, anti-microbial, anti-aging, anti-inflammatory and skin-lightening activities of wild-edible fruits of North-West Himalaya; Isolation and purification of bioactive compounds; development of effective formulations for general health maintenance and anti-aging, skin-whitening cosmetics and anti-cancer drug against cervical and breast cancers; Screening of medicinal plants for antibacterial activity against dental problems; Isolation and characterization of Natural compounds.

Soil Microbiology : Soil analysis; Isolation of stress (heavy metal, salts, temperature, pH) resistant bacterial species; Isolation of plant growth promoting bacteria; Development of biofertilizers for farmers.

Funded Projects

Title of the project	PI & Co-PI	Duration Year	Name of the funding Agency	Total grant sanctioned (Lakh)
“A probe into the Biodegradation Pathway for the High-Molecular Weight Polycyclic Aromatic Hydrocarbons (HMW-PAHs) by Bacillus subtilis BMT4i (MTCC 9447)”	Dr. Koushalya Dangwal	2007-2009	UCOST Uttarakhand	5.0
“Systematic screening of fourteen wild edible fruits of Uttarakhand for antitumor, antiaging, skin lightening and antioxidant agents.”	Dr. Koushalya Dangwal	2012-2015	Uttarakhand Council of Biotechnology Uttarakhand	6.03
“Biodegradation of a Potent Carcinogen Benzo [a] Pyrene (BaP) by Bacteria isolated from Automobile Contaminated Soil of hilly regions of Uttarakhand”	Dr. Koushalya Dangwal Co-PI – Dr. Madhuri K. Lily	2013-2016	DST, New- Delhi	24.10

Bacterial Gene Sequences deposited to National Center for Biotechnology Information (NCBI), USA

S. No.	GenBank Accession No.	Authors	Title	Year	Title
1.	DQ 911347	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Paenibacillus lautus (DMT637) 16S rRNA partial gene sequences	2006	Dibenzothiophene (DBT) desulfurization activities
2.	DQ 911348	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Bacillus subtilis (BMT4i) 16S rRNA partial gene sequences	2006	High molecular weight polyaromatic hydrocarbon (HMWPAHs) degradation
3	EU125186	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Brachybacterium paraconglomeratum (BMIT637C) 16S rRNA partial gene sequences	2007	HMWPAHs degradation
4.	EU125187	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Bacillus licheniformis BMIT5ii; 16S rRNA partial gene sequences	2007	HMWPAHs degradation
5	GQ496620	Ashutosh Bahuguna, Madhuri. K. Lily, Koushalya Dangwal	Lysinibacillus sphaericus DMT-7; 16S rRNA partial gene sequences	2010	Dibenzothiophene (DBT) desulfurization activites

Bacterial culture submitted to the MTCC, IMTECH, Chandigarh, India: Total 04

S. No.	MTTC Accession No.	Authors	Title	Year	Title
1.	MTCC9445	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Brachybacterium paraconglomeratum BMIT637C	2008	PAHs degradation activities
2.	MTCC 9446	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Bacillus licheniformis BMIT5ii	2008	PAH degrading activities
3.	MTCC9447	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Bacillus subtilis BMT4	2008	Benzo(a)pyrene degrading activities
4	MTCC9448	Madhuri. K. Lily, Ashutosh Bahuguna, Koushalya Dangwal	Paenibacillus lautus (DMT637)	2008	Dibenzothiophene (DBT) desulfurization activities

Doctoral Guidance

S.No.	Description	Total
1 .	Enrollment of Ph.D. Students	06
2.	Ph.D. degree awarded to the students	04
3.	Ph.D. thesis submitted	01
3.	Pursuing	01

Life Membership of Professional Bodies, Societies etc

Scientific Societies	Faculty Membership
Society of Biological Chemists (SBC), Indian Institute of Science (IISC), Bangalore, India	02
Indian Society of Cell Biologists (ISCB), Varanasi, India	01
Association of Microbiologists of India (AMI), New Delhi, India	03
National Science Congress	01
International Society of Zoological Science China	01
Hindi Vigyan Science Parishad, Mumbai	02

Expertise and Consultancy offered by the Department

DNA and RNA isolation and Estimation
PCR amplification, Blotting and hybridization (DNA, RNA and proteins),
Cell- free/Nuclear extracts preparation.
Quantitative analysis : Total proteins; lipids; carbohydrates; Organic carbons, Dietary fibers, Sterols, Phenolics and Flavonoids
Water quality analysis
Milk quality checking
Bioactivities analysis: Antioxidant activities (based on in vitro both enzymatic and non-enzymatic); Antimicrobial activities (antibacterial and antifungal)
Isolation and characterization of Natural compounds; essential oil;
Soil analysis
Analysis of effects of stress (heavy metal, salts, temperature, pH) on bacterial species
Analysis of plant growth promoting bacteria
Development of biofertilizers for farmers

Consultancy provided to the external and internal agency till date

C.R. Deb, Department of Botany; Nagaland University, Lumami-798 627.

“Nutritional analysis (total protein, dietary fibers and organic carbons) of mushroom samples” (May 2015)

Revenue Generated = Rs. 24,000/-

Modern Institute of Technology, Rishikesh; “Water Quality Analysis of various water sources” (every year since 2007 till date)
“Antimicrobial activity of plant samples” (March 2017) for Ms Meena Badola, Department of Botany and Microbiology , HNBG University Srinagar, Garhwal, Revenue generated =Rs. 1800/-

Research & Consultancy

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